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Robert J. Singer, MD, MS, FACS

rjsinger@mac.com

603-667-8173

emerald russell

website design

CONSULTING
RJS

PUBLICATIONS

Journal Articles:

1. Singer RJ, Norbash AM: Interventional neuroradiology: techniques, applications, and clinical issues. Int Anesthesiol Clin 34(4): 161-78, 1996 Jan. PMID:8956070

2. Abe T, Singer RJ, Marks MP, Kojima K, Watanabe M, Uchida M, Hayabuchi N: Arterial vascular abnormality accompanying cerebral cortical dysplasia. Amer J Neuroradiol 18(1): 144-6, 1997 Jan. PMID: 9010533

3. Singer RJ, Dake MD, Norbash AM, Abe T, Marcellus ML, Marks MP: Covered stent placement for neurovascular disease. Amer J Neuroradiol 18: 507-9, 1997 Mar. PMID: 9090412

4. Singer RJ, Abe T, Taylor WH, Marks MP, Norbash AM: Intracavernous anterior cerebral artery origin with associated arteriovenous malformation: a developmental analysis: Case report. Neurosurg 40(4): 829-31, 1997 Apr. PMID: 9092857

5. Abe T, Singer RJ, Marks MP, Norbash AM, Crowley R, Steinberg GK: Coexistence of occult vascular malformations and developmental venous anomalies in the central nervous system: MR evaluation. Amer J Neuroradiol 19(1): 51-7, 1998 Jan. PMID: 9432157

6. Abe T, Kojima K, Singer RJ, Marks MP, Watanabe M, Nishimura H, Hayabuchi N: Endovascular management of an aneurysm arising from posterior inferior cerebellar artery originated at the level of C2. Radiat Med 16(2): 141-3, 1998 Mar-Apr. PMID: 9650904

7. Singer RJ, Clough J, Johnson M, Copeland MJ: Pigmented schwannoma of the ventral spinal cord. South Med J 92(5): 545-47, 1999 May. PMID: 10342906

8. Norbash AM, Singer RJ: Videographic assessment of the embolic characteristics of three polymeric compounds: ethylene vinyl alcohol, cellulose acetate, and liquid urethane. AJNR Am J Neuroradiol 22(2): 334-40, 2001 Feb. PMID: 11156779

9. Ogilvy CS, Hoh BL, Singer RJ, Putman CM: Clinical and radiographic outcome in the management of posterior circulation aneurysms by use of direct surgical or endovascular techniques. Neurosurg 51(1): 14-21, 2002 Jul. PMID: 12182412

10. Alamanda VK, Tomycz L, Velez D, Singer RJ: Direct, high-flow bypass for a pediatric giant, fusiform aneurysm of the inferior division of M2: Case report and review of the literature. J Surg Tech Case Rep 4(1): 53-7, 2012 Jan. PMID:23066467

11. Jermakowicz WJ, Tomycz L, Ghiassi M, Singer RJ: Use of endovascular embolization to treat a ruptured arteriovenous malformation in a pregnant woman: A case report. J Med Case Rep 6: 113, 2012 Apr. PMID: 22524895

12. Tomycz L, Maris AS, Ghiassi M, Singer RJ: Open surgical disconnection for congenital, multi-hole, pial arteriovenous fistulae in non-eloquent cortex. Neurol India 60(4): 415-8, 2012 Jul-Aug. PMID:22954978

13. Martin JA, Maris AS, Ehtesham M, Singer RJ: Rat model of blood-brain barrier disruption to allow targeted neurovascular therapeutics. J Vis Exp 69: e50019, 2012 Nov. PMID:23222697

14. Tomycz L, Bansal NK, Lockney T, Strothers M, Connors JJ, Shay S, Singer RJ: Primary balloon angioplasty for symptomatic, high-grade intracranial stenosis. Surg Neurol Int 4: 18, 2013. [Epub 2013 Feb 20] PMID: 23493431

15. Narayanan S, Singer RJ, Abruzzo TA, Hussain MS, Powers CJ, Prestigiacomo CJ, Heck DV, Sunshine JL, Kelly M, Jayaraman MV, Meyers PM [on behalf of the Standards and Guidelines Committee of the Society of Neurointerventional Surgery]: Reporting standards for balloon test occlusion. J Neurointerv Surg 5(6): 503-5, 2013 Nov. [Epub 2013 June 22] PMID: 23794674

16. Donahue MJ, Ayad M, Moore R, van Osch M, Singer RJ, Clemmons P, Strother M: Relationships between hypercarbic reactivity, cerebral blood flow, and arterial circulation times in patients with moyamoya disease. J Magn Reson Imaging 38(5): 1129-39, 2013 Nov. [Epub 2013 Feb 25] PMID: 23440909

17. Ladner TR, Ehtesham M, Davis BJ, Khan IS, Ghiassi M, Ghiassi M, Singer RJ: Resolution of trigeminal neuralgia by coil embolization of a persistent primitive trigeminal artery aneurysm. BMJ Case Rep, bcr2013010703, 2013 Apr. PMID: 53625680

18. Grelli KN, Palubinsky AM, Kale AC, Lizama-Manibusan BN, Stankowski JN, Milne GL, Singer RJ, McLaughlin B: Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation. CNS Neurol Disord Drug Targets 12(6): 849-60, 2013 Sept. PMID: 23469839.

19. Zaiss M, Xu J, Goerke S, Khan IS, Singer RJ, Gore JC, Gochberg DF, Bachert P: Inverse Z-spectrum analysis for spillover-, MT, and T1- corrected steady-state pulsed CEST-MRI-application to pH-weighted MRI of acute stroke. NMR Biomed 27(3): 240-52, 2014 Mar. [Epub 2014 Jan 3] PMID: 24395553

20. Khan IS, Ladner TR, Satti KF, Ehtesham M, Jordan LC, Singer RJ: Endovascular thrombolysis for pediatric cerebral sinus venous thrombosis with tissue plasminogen activator and abciximab. J Neurosurg Pediatr 13(1): 68-71, 2014 Jan. [Epub 2013 Nov 1] PMID: 24180679

21. Khan IS, Kelly PD, Singer RJ: Prototyping of cerebral vasculature physical models. Surg Neurol Int 5: 11, 2014 Jan 27. PMID: 24678427

22. Khan IS, Kiehna EN, Satti KF, Ehtesham M, Ghiassi M, Singer RJ: Surgical management of large scalp infantile hemangiomas. Surg Neurol Int 5: 41, 2014 Mar 27. PMID: 24818048

23. Arteaga D, Strother M, Faraco CC, Jordan L, Ladner TR, Dethrage LM, Singer RJ, Mocco J, Clemmons PF, Donahue MJ: The vascular steal phenomenon is an incomplete contributor to negative cerebrovascular reactivity in patients with symptomatic intracranial stenosis. J Cereb Blood Flow Metabol 34(9):1453-62, 2014 Sep. [Epub 2014 Jun 11]

24. Ladner TR, Ehtesham M, Davis BJ, Khan IS, Ghiassi M, Ghiassi M, Singer RJ: Resolution of trigeminal neuralgia by coil embolization of a persistent primitive trigeminal artery aneurysm. J Neurointervent Surg 6(3): e22, 2014 Apr. [Epub 2013 May 3] PMID: 24610143

25. Strother MK, Anderson MD, Singer RJ, Du L, Moore RD, Shyr Y, Ladner TR, Arteaga D, Day MA, Clemmons PF, Donahue MJ: Cerebrovascular collaterals correlate with disease severity in adult North American patients with Moyamoya disease. AJNR Amer J Neuroradiol 35(7): 1318-24, 2014 Jul. [Epub 2014 Mar 20] PMID: 24651814

26. Donahue MJ, Jordan L, Clemmons PF, Singer RJ, Mocco J, Shyr Y, Desai AA, Oduffy AE, Riebau DA, Hermann L, Connors B, Kirshner H, Strother M: Routine clinical evaluation of cerebrovascular reserve capacity using carbogen in patients with intracranial stenosis. Stroke 45(8): 2335-41, 2014 Aug. [Epub 2014 Jun 17] PMID: 24938845

27. Ahn AK, Jordan L, Singer RJ, Honeybrook A: Stroke after Adenotonsillectomy in Patients with undiagnosed Moyamoya Syndrome. JAMA OtolaryngolHead Neck Surg 140(11): 1061-4, 2014 Nov. [Epub 2014 Sep 25] PMID: 25257069

28. Li H, Zu Z, Zaiss M, Khan IS, Singer RJ, Gore JC, Xu J: Imaging of amide proton transfer and nuclear overhauser effects in ischemic stroke with corrections for confounding effects. NMR Biomed 28(2): 200-9, 2015 Feb. [Epub 2014 Dec 7] PMID: 25483870

29. Zaidat OO, Fitzsimmons BF, Woodward BK, Wang Z, Killer-Oberpfalzer M, Wakhloo A, Gupta R, Kirshner H, Megerian JT, Lesko J, Pitzer P, Ramos J, Castonguay AC, Barnwell S, SmithWS, Gress DR, VISSIT Trial Investigators, Singer RJ (et al): Effect of a balloon-expandable intracranial stent vs medical therapy on risk of stroke in patients with symptomatic intracranial stenosis: The VISSIT randomized clinical trial. JAMA

313(12): 1240-8, 2015 Mar. PMID: 25803346

30. Palubinsky AM, Stankowski JN, Kale AC, Codreanu SG, Singer RJ, Liebler DC, Standwood GD, McLaughlin BM: CHIP is an essential determinant of neuronal mitochondrial stress signaling. Antioxid Redox Signal 23(6): 535-49, 2015 Aug. [Epub 2015 Mar 18] PMID: 25602369

31. Faraco CC, Detharge L, Jordan L, Clemmons PF, Singer RJ, Donahue MJ: Dual echo vessel-encoded ASL for simultaneous BOLD and CBF reactivity assessment in patients with ischemic cerebrovascular disease. Magn Reson Med 73(4): 1579-92, 2015 Apr. [Epub 2014 April 22] PMID: 24757044

32. Bekelis K, Missios S, Coy S, Singer RJ, MacKenzie T: New York State: Comparison of treatment outcomes for unruptured cerebral aneurysms using an instrumental variable analysis. J Am Heart Assoc 4(7): e002190, 2015 Jul. PMID: 26169534

33. Bekelis K, Missios S, Coy S, Rahmani R, Singer RJ, MacKenzie TA: Surgical clipping versus endovascular intervention for the treatment of subarachnoid hemorrhage patients in New York State. PLoS One 10(9): e0137946, 2015 Sept. PMID: 26360422

34. Khan IS, Odom M, Ehtesham M, Colvin D, Quarles CC, McLaughlin B, Singer RJ: Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities. J Neurosurg. [Epub ahead of print] PMID: 26544777

35. Bekelis K, Kerley-Hamilton JS, Teegarden A, Tomlinson CR, Kuintzle R, Simmons N, Singer RJ, Roberts DW, Kellis M, Hendrix DA: MicroRNA and gene expression changes in unruptured human cerebral aneurysms. J Neurosurg. [Epub ahead of print] PMID: 26918470 

 

Electronic Media:

1. Singer RJ: “I’ve Got a What?” General information for patients just diagnosed with a brain aneurysm. Brain Aneurysm Foundation educational series. Podcast, October 2012.

2. Khan IS, Singer RJ, Johnston M: Vein of galen malformations. MedLink Neurology, August 2013 www.medlink.com

3. Whitson WJ, Singer RJ, Johnston M: Hydrocephalus. MedLink Neurology, October 2013. www.medlink.com

4. Bekelis K, Singer RJ, Johnston M: Craniosynestosis. MedLink Neurology, October 2013. www.medlink.com

5. Whitson WJ, Singer RJ, Johnston M: Myelomeningocele. MedLink Neurology, October 2013. www.medlink.com

6. Monroe, P, Root B, Bekelis K, Singer RJ: External ventricular drain placement (Surgical Training Module), iOS application. Touch Surgery, June 2014. www.touchsurgery.com

7. Singer RJ, Khan IS, Root B: Carotid endarterectomy (Surgical Training Module), iOS application. Touch Surgery, July 2014. www.touchsurgery.com

8. Singer RJ, Morone P, Zuckerman S, Dewan M. Acute trauma craniotomy: Dartmouth. Surgical Simulation Application, Touch Surgery, February 2015. www.touchsurgery.com

9. Rahmani R, Root B, Singer RJ, Maria B: Leigh syndrome. MedLink Neurology, February 2015. www.medlink.com

10. Porras J, Root B, Singer RJ, Maria B: Childhood lead poisoning. MedLink Neurology, February 2015. www.medlink.com

11. Root B, Singer RJ: The case for a virtual brain aneurysm clinic. Web blog post. Brain Aneurysm Foundation, August 2015. http://www.bafound.org/blog/case-virtual-brain-aneurysm-clinic

12. Bekelis K, Singer RJ: Fragile X syndrome. Medlink Neurology, January 2016. www.medlink.com

13. Bekelis K, Singer RJ: Breath-holding spells. Medlink Neurology, January 2016. www.medlink.com

14. Bekelis K, Singer RJ: Kawasaki disease. Medlink Neurology, January 2016. www.medlink.com

15. Bekelis K, Singer RJ: Congenital syphilis. Medlink Neurology, January 2016. www.medlink.com

16. Bekelis K, Singer RJ: PANDAS. Medlink Neurology, January 2016. www.medlink.com

17. Bekelis K, Singer RJ: Child maltreatment. Medlink Neurology, January 2016. www.medlink.com

18. Bekelis K, Singer RJ: Chorea in childhood. Medlink Neurology, January 2016. www.medlink.com

19. Bekelis K, Singer RJ: Spasticity. Medlink Neurology, January 2016. www.medlink.com

20. Bekelis K, Singer RJ: Hemimegalencephaly. Medlink Neurology, January 2016. www.medlink.com

21. Bekelis K, Singer RJ: Acute hemiplegia in childhood. Medlink Neurology, January 2016. www.medlink.com

22. Bekelis K, Singer RJ: Intellectual disability. Medlink Neurology, January 2016. www.medlink.com

 

Reviews/Comments/Letters to Editor:

1. Singer RJ, Ogilvy CS: Invited Comment. Murayama Y, Viñuela F, Duckwiler GR, Gobin YP, Guglielmi G: Endovascular embolization of 150 basilar tip aneurysms with Gugliemi detachable coils: Results of the FDA multicenter clinical trial. Neurosurg Focus, 5(4): E4, 1998 Oct.

2. Singer RJ, Jordan LC: Brain arteriovenous malformations in adults and children. Tenn Fam Physician Summer Edition, 2012.

 

Book Chapters:

1. Singer RJ, Standard SC. Endovascular Treatment of Central Nervous System Metastases. In Maciunas RJ (ed): Advanced Techniques in Central Nervous System Metastases. AANS Neurosurgical Topics Series, Park Ridge, IL: Library of Congress, 1998.

2. Norbash AM, Singer RJ: Interventional neuroradiologic therapy. In Anesthesiologists Manual of Surgical Procedures. New York: Raven Press, 1997.

3. Singer RJ, Ogilvy CS: Surgical management of hyperacute stroke. In Hyperacute Stroke: Imaging and Intervention. Oxford: Isis Medical Media Limited, 1998.

4. Singer RJ, Ogilvy CS: Management of dissections of the carotid and vertebral arteries. In Schmidek HH, Sweet WH (eds): Operative Neurosurgical Techniques, 4th Edition, Philadelphia, PA: W.B. Saunders Co, 2000, pp 1085-92.

5. Loeffler JS, Singer RJ, Chapman PH, Ogilvy CS: Proton beam radiation therapy. In Germano IM (ed): Linac and Gamma Knife Radiosurgery, AANS Neurosurgical Topics Series, Park Ridge, IL: Library of Congress, 2000.

6. Singer RJ, Rordorf G, Ogilvy CS: Subarachnoid hemorrhage; diagnosis and Management. In UpToDate Neurology, Wellesley, MA, 2000.

7. Singer RJ, Rordorf G, Ogilvy CS: The intracranial neurovasculature: Congenital malformations. In UpToDate Neurology, Wellesley, MA, 2000.

8. Singer RJ, Norbash AM, Standard SC: Angioplasty and Stenting of the Neurovasculature. In Maciunas R (ed): Neural Prostheses, AANS Neurosurgical Topics Series, Park Ridge, IL, 2000.

9. Hoh BL, Singer RJ, Carter BS, Ogilvy CS: Management of dissections of the carotid and vertebral arteries. In Schmidek HH, Roberts DW (eds): Operative Neurosurgical Techniques, 5th Edition. Philadelphia, PA: W.B. Saunders, 2006, pp 1061-74.

10. Reig A, Singer RJ: Spinal vascular malformations. In Biller J, Wilterdink JL (eds): UpToDate Neurology, Wolters Kluwer Publishers, Wellesley, MA, 2010.

11. Singer RJ, Ogilvy CS, Rordorf G: Subarachnoid hemorrhage grading scales. In Biller J, Wilterdink JL (eds): UpToDate Neurology, Wolters Kluwer Publishers, Wellesley, MA, 2011. Update: Jan 5, 2012.

12. Singer RJ, Ogilvy CS, Rordorf G: Vascular malformations of the central nervous system. In Biller J, Wilterdink JL (eds): UpToDate Neurology, Wolters Kluwer Publishers, Wellesley, MA, 2011. Update: May 3, 2012.

13. Singer RJ, Ogilvy CS, Rordorf G: Brain arteriovenous malformations. In Biller J, Wilterdink JL (eds): UpToDate Neurology, Wolters Kluwer Publishers, Wellesley, MA, 2011. Update: May 3, 2012.

14. Ball PA, Bekelis K, Root B, Khan IS, Singer RJ. Principles of neurocritical care. (Submitted to Youmans and Winn Neurological Surgery, 7th Edition)

 

Published Abstracts:

1. Singer RJ, Ogilvy CS: Risks and Efficacy of Combined Endovascular and Surgical Management of

Intracranial Dural Arteriovenous Malformations. Stroke 30(1): 271, 1999.

2. Palubinsky, AM, Codreanu, SG, Singer RJ, Liebler, DJ, and McLaughlin, B: Role of C-terminus of HSC70 interacting protein (CHIP) in mediating ischemic preconditioning. Society for Neuroscience. San Diego, CA, 2013, Nov.